BRIN Develops Noninvasive Glucose Monitoring Technology

RRI.CO.ID, South Tangerang - The National Research and Innovation Agency (BRIN) developed a sensor based on Surface Plasmon Resonance (SPR) that has potential to detect glucose levels noninvasively, rapidly, and in real time. The innovation was a response to the growing need for more comfortable and practical blood glucose monitoring technology alongside the rising number of people living with diabetes worldwide.

The innovation was presented by Lia Aprilia, Associate Research Professor at the Photonics Research Center of the National Research and Innovation Agency, during the Scientific and Innovation Presentation Forum ORNAMAT #87 held online on recenty. "Monitoring glucose levels remains highly important, especially for people with diabetes whose numbers continue increasing annually," Lia said as quoted ny BRIN's website on Friday, June 26, 2026.

Based on data from the International Diabetes Federation (IDF), the global number of people living with diabetes is projected to reach 700 million by 2030. This condition encourages the development of glucose monitoring technologies that are easier, more accurate, and more comfortable for public use.

“Current glucose monitoring methods are still invasive because they require blood samples. Besides causing pain and discomfort, the analysis process also requires time,” she said.

As a solution, Lia stated that BRIN developed sensor technology based on Surface Plasmon Resonance, an optoelectronic sensing technology capable of detecting refractive index changes resulting from biomolecular interactions on thin metal surfaces. This technology is recognized for its high sensitivity, label-free capability, and ability to monitor biomolecular interactions in real time.

Lia explained that the operating principle of SPR enables precise biomolecular detection and therefore shows strong potential for future-generation glucose monitoring devices. The technology is considered promising for creating more practical healthcare monitoring solutions for routine daily use.

Moreover, she added that SPR has the potential to become an accurate and comfortable glucose sensing platform that can be integrated into various everyday health monitoring applications. The development of SPR-based sensors also represents BRIN’s broader effort to provide more effective and user-friendly diagnostic technologies.

Beyond creating opportunities for noninvasive glucose monitoring devices, this research strengthens national capabilities in photonics and biosensor development. Looking ahead, the technology is expected to support more efficient, affordable, and innovation-based healthcare services while improving quality of life for people requiring regular glucose monitoring.